Overview

SCIENTIFIC SCORE
Questionable
Based on 5 Researches
5.6
USERS' SCORE
Good
Based on 126 Reviews
8.2
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Inositol
500 mg
**

Top Medical Research Studies

8
Myo-inositol enhances vitamin D effects
Our study aimed to explore the impact of myo-inositol treatment on thyroid autoimmunity in women with autoimmune thyroiditis. We included groups of women who had been on myo-inositol for a while and those who hadn’t. For six months, we observed how vitamin D supplementation interacted with myo-inositol in affecting thyroid health and immune responses.

We found that among participants taking myo-inositol, the addition of vitamin D significantly improved insulin sensitivity and led to better outcomes regarding thyroid antibodies. Specifically, women who were already on myo-inositol showed a greater reduction in thyroid peroxidase and thyroglobulin antibodies when vitamin D was added to their regimen.

Interestingly, the effects of vitamin D were less noticeable in women who weren't on myo-inositol. These individuals did not exhibit the same improvements in thyroid function or antibodies. Overall, the findings suggest that myo-inositol might enhance the benefits of vitamin D, indicating a potential synergistic effect between these two agents in managing autoimmune thyroiditis.
Read More
We aimed to understand the impact of Myo-inositol on thyroid autoantibody levels in patients with Hashimoto's thyroiditis (HT). Our analysis included data from a systematic review of several case-control studies that explored various dietary supplements, particularly focusing on inositol's effectiveness.

Our findings revealed that while selenium supplementation significantly reduced thyroid autoantibodies, the effects of Myo-inositol were not as promising. In fact, Myo-inositol, as well as Vitamin D both alone and in combination with selenium, did not produce significant reductions in either thyroid peroxidase autoantibodies (TPOAb) or thyroglobulin autoantibodies (TgAb).

This lack of efficacy suggests that Myo-inositol may not be an effective standalone treatment for lowering autoantibody levels in autoimmune disorders like HT. Therefore, we recommend that patients focus on selenium as a more impactful supplement during their treatment journey.
Read More
4
Inositol's impact on autoimmune thyroid
We set out to explore the effects of a combination of selenium and inositol on thyroid function and autoimmune characteristics in people with thyroid disorders. Through our systematic search spanning numerous databases, we reviewed studies published from 2007 to 2022, focusing on how these supplements influence thyroid health.

The results were somewhat mixed. While our findings indicated a modest increase in levels of Triiodothyronine (T3) after using both supplements, this change was not statistically significant. However, we did observe a significant increase in Thyroxine (T4) levels and a notable decrease in Thyroid-stimulating hormone (TSH), which suggests potential positive outcomes. It's important to note that the levels of Anti-Thyroid Peroxidase Antibodies (TPOAb) did not show any significant change, and the overall improvements in T3 levels were not enough to substantiate a clear benefit.

Overall, our investigation reveals that adding inositol to selenium might not dramatically alter the thyroid's autoimmune activity. Still, the decrease in TSH and increase in T4 could hint at potential benefits that warrant further exploration. Given the limited number of studies in this area, more research will be essential to fully understand how inositol may affect autoimmune disorders related to thyroid health.
Read More

Most Useful Reviews

10
Supports fertility
150 people found this helpful
Excellent! It helped me get pregnant! I ordered several courses for a friend who was struggling but eventually achieved a long-awaited pregnancy due to ovulation disorder. This product is effective!
Read More
9
Effective alternative
63 people found this helpful
This product has proven to be an excellent substitute for Inofert, which I used for multifollicular ovaries before IVF. Taking inositol alongside folic acid has positively influenced my cycle and helped decrease ovarian size. I will carry on with this for a few more months.
Read More
9
Restored ovulation
63 people found this helpful
After being diagnosed with polycystosis, I struggled with inconsistent ovulation, until I discovered inositol, which I learned is vital for addressing my autoimmune disorder. With consistent intake of one tablet twice daily, my ovaries returned to a healthy size, and ovulation resumed. I had not expected such results, and I highly recommend it to anyone facing similar challenges with PCOS!
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 5 Researches
5.6
  • All Researches
Our exploration focused on how Myoinositol, often known as Myo, impacts autoimmune disorders, particularly autoimmune thyroiditis. We learned that Myo plays a crucial role in the body's thyroid function by aiding in the production of thyroid hormones and regulating iodine, which is essential in this process.

Interestingly, when Myo was combined with Selenium in treatment, patients with subclinical hypothyroidism showed significant decreases in thyroid-stimulating hormone (TSH) levels. Additionally, levels of antithyroid autoantibodies also dropped, which is promising for those battling autoimmune thyroid issues.

However, it is important to note that the study did not exclusively isolate the effect of Myoinositol, as the results were observed in conjunction with Selenium. Therefore, while the findings are encouraging, we cannot definitively claim that Myo alone yields the same benefits in managing autoimmune disorders.
Read More
8
Myo-inositol enhances vitamin D effects
Our study aimed to explore the impact of myo-inositol treatment on thyroid autoimmunity in women with autoimmune thyroiditis. We included groups of women who had been on myo-inositol for a while and those who hadn’t. For six months, we observed how vitamin D supplementation interacted with myo-inositol in affecting thyroid health and immune responses.

We found that among participants taking myo-inositol, the addition of vitamin D significantly improved insulin sensitivity and led to better outcomes regarding thyroid antibodies. Specifically, women who were already on myo-inositol showed a greater reduction in thyroid peroxidase and thyroglobulin antibodies when vitamin D was added to their regimen.

Interestingly, the effects of vitamin D were less noticeable in women who weren't on myo-inositol. These individuals did not exhibit the same improvements in thyroid function or antibodies. Overall, the findings suggest that myo-inositol might enhance the benefits of vitamin D, indicating a potential synergistic effect between these two agents in managing autoimmune thyroiditis.
Read More
We aimed to understand the impact of Myo-inositol on thyroid autoantibody levels in patients with Hashimoto's thyroiditis (HT). Our analysis included data from a systematic review of several case-control studies that explored various dietary supplements, particularly focusing on inositol's effectiveness.

Our findings revealed that while selenium supplementation significantly reduced thyroid autoantibodies, the effects of Myo-inositol were not as promising. In fact, Myo-inositol, as well as Vitamin D both alone and in combination with selenium, did not produce significant reductions in either thyroid peroxidase autoantibodies (TPOAb) or thyroglobulin autoantibodies (TgAb).

This lack of efficacy suggests that Myo-inositol may not be an effective standalone treatment for lowering autoantibody levels in autoimmune disorders like HT. Therefore, we recommend that patients focus on selenium as a more impactful supplement during their treatment journey.
Read More
4
Inositol's impact on autoimmune thyroid
We set out to explore the effects of a combination of selenium and inositol on thyroid function and autoimmune characteristics in people with thyroid disorders. Through our systematic search spanning numerous databases, we reviewed studies published from 2007 to 2022, focusing on how these supplements influence thyroid health.

The results were somewhat mixed. While our findings indicated a modest increase in levels of Triiodothyronine (T3) after using both supplements, this change was not statistically significant. However, we did observe a significant increase in Thyroxine (T4) levels and a notable decrease in Thyroid-stimulating hormone (TSH), which suggests potential positive outcomes. It's important to note that the levels of Anti-Thyroid Peroxidase Antibodies (TPOAb) did not show any significant change, and the overall improvements in T3 levels were not enough to substantiate a clear benefit.

Overall, our investigation reveals that adding inositol to selenium might not dramatically alter the thyroid's autoimmune activity. Still, the decrease in TSH and increase in T4 could hint at potential benefits that warrant further exploration. Given the limited number of studies in this area, more research will be essential to fully understand how inositol may affect autoimmune disorders related to thyroid health.
Read More
4
Myo-inositol shows inconclusive results
We explored the effects of myo-inositol as part of a treatment regimen for young women with Hashimoto's thyroiditis—an autoimmune disorder. This study primarily compared the sexual functioning and depressive symptoms of women who were untreated versus those receiving various supplements including vitamin D and selenomethionine alongside myo-inositol.

While all treatment groups showed improved sexual functioning and well-being compared to the untreated women, we observed that the greatest benefits came from those receiving vitamin D. Additionally, there were no significant differences in sexual functioning and depressive symptoms between the myo-inositol and selenomethionine treatment groups.

As a result, we must note that myo-inositol's isolated effect was not clearly determined in this study due to its combination with other treatments. Therefore, while myo-inositol is seen as part of a broader therapy, its specific influence on autoimmune disorders warrants further investigation.
Read More

User Reviews

USERS' SCORE
Good
Based on 126 Reviews
8.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
10
Supports fertility
150 people found this helpful
Excellent! It helped me get pregnant! I ordered several courses for a friend who was struggling but eventually achieved a long-awaited pregnancy due to ovulation disorder. This product is effective!
Read More
9
Effective alternative
63 people found this helpful
This product has proven to be an excellent substitute for Inofert, which I used for multifollicular ovaries before IVF. Taking inositol alongside folic acid has positively influenced my cycle and helped decrease ovarian size. I will carry on with this for a few more months.
Read More
9
Restored ovulation
63 people found this helpful
After being diagnosed with polycystosis, I struggled with inconsistent ovulation, until I discovered inositol, which I learned is vital for addressing my autoimmune disorder. With consistent intake of one tablet twice daily, my ovaries returned to a healthy size, and ovulation resumed. I had not expected such results, and I highly recommend it to anyone facing similar challenges with PCOS!
Read More
9
Enhanced fertility support
50 people found this helpful
At 37, we are trying for our second child. Inositol is vital in forming follicles and quality oocytes. Its use in pre-gestational preparation improves outcomes in assisted reproductive technologies (ART), reducing the doses of rFSH needed and the duration of stimulation, ultimately lowering the risk of ovarian hyperstimulation syndrome. Inositol and folate can also reduce hormonal loads while improving the quality of oocytes and embryos without affecting clinical pregnancy rates. Studies show significant increases in pregnancy frequency across ART protocols using inositol.
Read More
9
Achieved natural ovulation
47 people found this helpful
In my efforts to conceive, doctors diagnosed me with PCOS and recommended hormone therapy, stating my only options were IVF with AI. I researched extensively and decided to order Inositol, ovariamine, vitamins, and more. After a month of treatment, I began ovulating naturally and subsequently became pregnant.
Read More

Frequently Asked Questions

9
Achieved natural ovulation
47 people found this helpful
In my efforts to conceive, doctors diagnosed me with PCOS and recommended hormone therapy, stating my only options were IVF with AI. I researched extensively and decided to order Inositol, ovariamine, vitamins, and more. After a month of treatment, I began ovulating naturally and subsequently became pregnant.
9
Period regularity
36 people found this helpful
Excellent! I used it for a month, and my period returned after two weeks without pills. It had been gone for a month and a half prior. Initially, I experienced light spotting for the first three days, but that was it. After finishing a box, I ordered two more and will provide an update next month. Thankfully, my LH hormone level returned to normal, and I feel better.
9
Improved chances of conception
32 people found this helpful
My friend had been trying to conceive for seven years and was advised to take inositol alongside other supplements. After a week, she shared the wonderful news of her pregnancy! Her stress levels have decreased significantly, making her feel much better overall. This demonstrates inositol's effectiveness for those dealing with fertility challenges linked to autoimmune disorders.
9
Restored ovulation
63 people found this helpful
After being diagnosed with polycystosis, I struggled with inconsistent ovulation, until I discovered inositol, which I learned is vital for addressing my autoimmune disorder. With consistent intake of one tablet twice daily, my ovaries returned to a healthy size, and ovulation resumed. I had not expected such results, and I highly recommend it to anyone facing similar challenges with PCOS!
9
Effective alternative
63 people found this helpful
This product has proven to be an excellent substitute for Inofert, which I used for multifollicular ovaries before IVF. Taking inositol alongside folic acid has positively influenced my cycle and helped decrease ovarian size. I will carry on with this for a few more months.
9
Health improvement
2 people found this helpful
I've been taking inositol with other supplements prescribed by my gynaecologist endocrinologist for two years. My analyses keep improving with each visit. The number of cysts in my breasts has decreased and my thyroid condition has improved. Overall, I feel calmer and less tearful. I will continue ordering this product!
9
Cycle regulation
2 people found this helpful
Inositol has significantly helped regulate my menstrual cycle and alleviate PMS symptoms. Originally, my gynaecologist prescribed COCs, but I switched to inositol. Since I started taking it, my cycle and its duration returned to normal, PMS symptoms vanished, and irritability and tearfulness ceased. My teenage daughter also experienced relief from PMS while taking it. I noted an even better outcome when inositol was combined with lecithin, especially avoiding soy lecithin for autoimmune conditions. This product gently restored my cycle entirely.
9
Ovulation improvement achieved
25 people found this helpful
For those struggling with polycystic ovary syndrome (PCOS), I found inositol to be an excellent aid. Having faced challenges in conceiving, I chose this due to its appealing price compared to pharmacy alternatives like Fertina. I began taking 3000 mg daily, and by day 13, I had a dominant follicle of 21mm, progressing to a good yellow body by day 16. This supplement has significantly stimulated my ovaries, and I intend to continue its use to enhance oocyte quality for ART.
We aimed to understand the impact of Myo-inositol on thyroid autoantibody levels in patients with Hashimoto's thyroiditis (HT). Our analysis included data from a systematic review of several case-control studies that explored various dietary supplements, particularly focusing on inositol's effectiveness.

Our findings revealed that while selenium supplementation significantly reduced thyroid autoantibodies, the effects of Myo-inositol were not as promising. In fact, Myo-inositol, as well as Vitamin D both alone and in combination with selenium, did not produce significant reductions in either thyroid peroxidase autoantibodies (TPOAb) or thyroglobulin autoantibodies (TgAb).

This lack of efficacy suggests that Myo-inositol may not be an effective standalone treatment for lowering autoantibody levels in autoimmune disorders like HT. Therefore, we recommend that patients focus on selenium as a more impactful supplement during their treatment journey.
4
Myo-inositol shows inconclusive results
We explored the effects of myo-inositol as part of a treatment regimen for young women with Hashimoto's thyroiditis—an autoimmune disorder. This study primarily compared the sexual functioning and depressive symptoms of women who were untreated versus those receiving various supplements including vitamin D and selenomethionine alongside myo-inositol.

While all treatment groups showed improved sexual functioning and well-being compared to the untreated women, we observed that the greatest benefits came from those receiving vitamin D. Additionally, there were no significant differences in sexual functioning and depressive symptoms between the myo-inositol and selenomethionine treatment groups.

As a result, we must note that myo-inositol's isolated effect was not clearly determined in this study due to its combination with other treatments. Therefore, while myo-inositol is seen as part of a broader therapy, its specific influence on autoimmune disorders warrants further investigation.
8
Myo-inositol enhances vitamin D effects
Our study aimed to explore the impact of myo-inositol treatment on thyroid autoimmunity in women with autoimmune thyroiditis. We included groups of women who had been on myo-inositol for a while and those who hadn’t. For six months, we observed how vitamin D supplementation interacted with myo-inositol in affecting thyroid health and immune responses.

We found that among participants taking myo-inositol, the addition of vitamin D significantly improved insulin sensitivity and led to better outcomes regarding thyroid antibodies. Specifically, women who were already on myo-inositol showed a greater reduction in thyroid peroxidase and thyroglobulin antibodies when vitamin D was added to their regimen.

Interestingly, the effects of vitamin D were less noticeable in women who weren't on myo-inositol. These individuals did not exhibit the same improvements in thyroid function or antibodies. Overall, the findings suggest that myo-inositol might enhance the benefits of vitamin D, indicating a potential synergistic effect between these two agents in managing autoimmune thyroiditis.
4
Inositol's impact on autoimmune thyroid
We set out to explore the effects of a combination of selenium and inositol on thyroid function and autoimmune characteristics in people with thyroid disorders. Through our systematic search spanning numerous databases, we reviewed studies published from 2007 to 2022, focusing on how these supplements influence thyroid health.

The results were somewhat mixed. While our findings indicated a modest increase in levels of Triiodothyronine (T3) after using both supplements, this change was not statistically significant. However, we did observe a significant increase in Thyroxine (T4) levels and a notable decrease in Thyroid-stimulating hormone (TSH), which suggests potential positive outcomes. It's important to note that the levels of Anti-Thyroid Peroxidase Antibodies (TPOAb) did not show any significant change, and the overall improvements in T3 levels were not enough to substantiate a clear benefit.

Overall, our investigation reveals that adding inositol to selenium might not dramatically alter the thyroid's autoimmune activity. Still, the decrease in TSH and increase in T4 could hint at potential benefits that warrant further exploration. Given the limited number of studies in this area, more research will be essential to fully understand how inositol may affect autoimmune disorders related to thyroid health.

References

  1. Peng B, Wang W, Gu Q, Wang P, Teng W, et al. Effects of different supplements on Hashimoto's thyroiditis: a systematic review and network meta-analysis. Front Endocrinol (Lausanne). 2024;15:1445878. doi:10.3389/fendo.2024.1445878
  2. Yavari M, Akbari M, Ramezani Ahmadi A, Siavash Dastjerdi M, Hashemi MS. Investigating the effect of combined use of selenium and Myo-inositol supplements on thyroid function and autoimmune characteristics in thyroid disorders: a systematic review and meta-analysis. Expert Rev Endocrinol Metab. 2024;19:269. doi:10.1080/17446651.2023.2295487
  3. Krysiak R, Kowalcze K, Szkróbka W, Okopień B. Sexual Function and Depressive Symptoms in Young Women with Euthyroid Hashimoto's Thyroiditis Receiving Vitamin D, Selenomethionine and Myo-Inositol: A Pilot Study. Nutrients. 2023;15. doi:10.3390/nu15122815
  4. Paparo SR, Ferrari SM, Patrizio A, Elia G, Ragusa F, et al. Myoinositol in Autoimmune Thyroiditis. Front Endocrinol (Lausanne). 2022;13:930756. doi:10.3389/fendo.2022.930756
  5. Krysiak R, Kowalcze K, Okopień B. The impact of vitamin D on thyroid autoimmunity and hypothalamic-pituitary-thyroid axis activity in myo-inositol-treated and myo-inositol-naïve women with autoimmune thyroiditis: A pilot study. J Clin Pharm Ther. 2022;47:1759. doi:10.1111/jcpt.13730
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